Ironwood Pharmaceuticals Inc. is moving its headquarters, from the biotech mecca of Cambridge’s Kendall Square to downtown Boston, and downsizing its space by nearly two-thirds. 

Ironwood (Nasdaq: IRWD) will lease 39,000 square feet at 100 Summer St. through 2030, and the company anticipates moving in by the end of the year.

The commercial-stage biotech company currently leases 108,000 square feet of office space at 301 Binney St., a facility in Kendall Square. The 417,290-square-foot facility…

Boston Biz Journal